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RESEARCH USE ONLY · NOT FOR HUMAN CONSUMPTION · INFORMATIONAL MATERIAL
Handling guide

Handling the pen in three phases

For anyone who has already decided to use the pen: a simple guide to handling it safely, from the box to throwing away the needle. The dose and frequency are always set by a healthcare professional; follow the manufacturer’s instructions as well.

Handling guide

Four parts worth knowing

Window of the VLS pen

Pen window

The window where the chosen setting appears. Check it every time before injecting: it must match what your professional indicated.

3 mL reservoir of the pen

3 mL multi-dose reservoir

A single reservoir lasts for several uses; from one use to the next, only the needle is replaced.

Cap of the pen

Cap

Covers the tip of the pen and the window, protecting them while the pen is not in use. To inject, unscrew the cap.

3 mm needle for the pen

3 mm needle

Short, designed for the subcutaneous tissue. The box holds 4 needles of 3.0 mm, and each is used once only.

Illustrative images.

Handling guide

Three phases, start to finish

  1. 1

    Prepare

    Wash your hands and look at the solution; if its appearance has changed in any way, do not use it. Check the seal, batch and expiry date on the box, and gather everything before you begin: your professional’s instruction, a new needle and the sharps bin.

  2. 2

    Use

    Fit a new needle and take off its protective cap. With the pen ready, confirm in the window that the setting is the one your professional indicated, without changing it yourself. The injection is subcutaneous and follows what your professional showed you and what the manufacturer’s instructions say.

  3. 3

    Close

    Remove the needle and put it straight into a rigid sharps container. Put the cap back on the pen and return it to the refrigerator, between 2 and 8 °C, until its next use.

Handling guide

Where and how, card by card

Swipe to see the reference sites for a subcutaneous injection and each step, from getting ready to throwing the needle away.

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  • Illustration: Area of the abdomen for a subcutaneous injection, away from the navelSite

    Abdomen, away from the navel

    Between the ribs and the hip bones, leaving at least 5 cm (about three finger-widths) clear around the navel.

  • Illustration: Front of the upper thigh for a subcutaneous injectionSite

    Thigh, upper half

    On the upper half of the thigh, at the front or towards the outer side, away from the knee and the groin.

  • Illustration: Back of the upper arm for a subcutaneous injectionSite

    Arm, back or side

    On the upper half of the arm, at the back or the side, about 7.5 cm (four finger-widths) from the shoulder and from the elbow.

  • Illustration: Clean hands, cotton and alcohol next to the penStep 1

    Get ready

    Wash your hands, check that the solution is clear and free of particles, and clean the skin at the site with cotton and alcohol. Let it dry.

  • Illustration: Pen with a new needle, ready for a subcutaneous injectionStep 2

    Inject

    With a new needle fitted and the window checked, the injection goes under the skin, at the chosen site and with the technique your professional showed you.

  • Illustration: Used needle thrown into a rigid containerStep 3

    Remove and throw away

    When you finish, take the needle off and drop it straight into a rigid container with a lid. Cap the pen and put it back in the refrigerator.

  • New 3 mm needle in its packagingAlways

    Never reuse a needle

    Every injection takes a new needle: a used one loses its sharpness and can carry germs into the skin. The pen is never shared either.

Reference sites for subcutaneous injection according to MedlinePlus (US National Library of Medicine) and the instructions for pens in this same class. It helps to change the spot each time, at least 2.5 cm from the last one. The exact site and technique are set by your professional, together with the manufacturer’s instructions. Illustrative images.

Illustration: VLS pen box with seal, batch number and expiry date

When the box arrives

  • The seal is intact and the code on the box can be checked on the verification page.
  • The batch number and expiry date printed on the box are legible.
  • Inside are the pen and the 4 needles of 3.0 mm.
  • From the moment it arrives, the pen is kept in the refrigerator, between 2 and 8 °C.
Illustration: Used needles kept in a rigid disposal containerCaution

Safe handling

  • Every injection uses a new needle; a used one is never fitted again.
  • The pen is personal: it is not shared, even with a fresh needle.
  • Do not freeze it; if it has frozen, do not use it.
  • Keep it well out of the reach of children and animals.

Illustrative images.

Handling guide

The peptide is delicate: handled with care, it keeps its potency

Retatrutide is a chain of amino acids dissolved in the liquid inside the pen. Treated roughly, those chains stick together or break apart and the pen loses potency, even if the liquid looks the same. Four habits prevent it:

Don’t shake it hard

Shaking makes foam, and at the bubbles the chains unfold and clump together. Gentle movements, always.

Never in the freezer

Ice damages the structure of the peptide. If it froze, don’t use it, even if it looks normal afterwards.

Away from light and heat

Inside its box, out of direct sun and away from the oven or a car parked in the sun.

Back in the refrigerator

After each use it goes back in the refrigerator, at 2 to 8 °C. Leaving it out keeps chipping away at its strength.

Why it happens and how to store it well

Got the box in your hand?

Check the code on the packaging at the manufacturer’s official page, or send us the batch number on WhatsApp.